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HashiScript® promotes healthy thyroid function, TPO levels and immune balancing.* It is a patented formula that blends 2 forms of glutathione one of which is the unique brand called Setria® glutathione, which has been shown to increase Natural Killer cell activity two-fold* HashiScript also contains protease enzymes for digestion, along with minerals, and antioxidants.

HashiScript® contains digestive enzymes which supports food metabolism, especially in the presence of high intestinal permeability.* The special blend of ingredients are thoughtfully placed into acid-resistant capsules for exceptional tolerability and absorption.* The addition of DPP-IV is a unique, and effective way to help those suffering with intestinal permeability issues, specifically those involving gluten and casein. 

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Vitamin D an immuno-supportive antioxidant 

Selenium a mineral antioxidant

Bromelain is a pineapple-derived digestive protease enzyme

Setria® Reduced Glutathione for body health and antioxidant protection

S-acetyl Glutathione for brain health it can penetrate the blood-brain barrier

Catalase an antioxidant for peroxide breakdown

Pancreatin enzyme for more comfortable enhanced protein digestion

BioCore® DPP-IV Protease enzyme to help reduce dairy and gluten absorption

Pepsin supports protein digestion

DR™ Caps Acid Resistant Capsules to protect the contents, as the formula passes through your stomach 


Take 2 capsules daily without regard to meals. You can take 2 capsules at the same time, or separately during the day. May be taken without regard to meals. One bottle contains 60 capsules. 


Q:  Can I take HashiScript if I have an autoimmune condition?
A:  HashiScript is a blend of antioxidants and digestive enzymes that support immune function and promote the metabolism of food.*  This in turn supports healthy antibody levels.*  Since we don’t know what’s right for every individual, we always advise that if you have a chronic health condition, then you should ask your health-care practitioner about taking any new supplement.

A:  Will I have to take HashiScript forever or can it be discontinued?
Q:  You can stop anytime you like.  If you decide you felt better when you were taking it, then start back up again.  There is no need to “wean” yourself off it either, so you can start or stop taking it suddenly if you choose to.  HashiScript should be thought of as an enzyme blend with special antioxidants* – it is not a drug nor does it contain any type of thyroid hormone.

Q:  What is the main difference between HashiScript and Thyroid Script?
A:  HashiScript is better to take if your immune system is involved.  Thyroid Script is better to take if your adrenal glands are involved.  Both formulas are intended to help support the thyroid gland.*  Both products are non-glandular formulas.  So both products can help if you have low thyroid function.*

Q:  What do the different ingredients do in HashiScript and Thyroid Script?
A:  The ingredients are totally different between these formulas.  Thyroid Script contain a very small amount of iodine, whereas HashiScript is iodine-free. Thyroid Script supports adrenal health because it contains ashwagandha, whereas HashiScript does not.* 

On the other hand, HashiScript contains proteolytic enzymes that help if you have increased intestinal permeability, which is often seen in individuals who have autoimmune dysfunction.*  HashiScript supports a healthy immune system, whereas Thyroid Script supports healthy adrenal glands and thyroid function but does not address immunity.*    

Q:  Can I take both HashiScript and Thyroid Script?
A:  Yes, if you would like to.  Thyroid Script supports healthy levels of thyroid hormone, as well as adrenal gland function; for example, in case you’re experiencing stress.*  HashiScript is an iodine-free blend of digestive enzymes and antioxidants that support healthy levels of peroxide.*  The reason for taking HashiScript would be to help support immune system function and maintain healthy levels of antibodies.* 

Q:  Glutathione gets destroyed in stomach acid.  Does that happen with HashiScript?
A:  No. There are two forms of glutathione in HashiScript, one is acetylated and one is “reduced.”  We include both forms of these potent antioxidants in a unique acid-resistant capsule to ensure the most effective delivery in the body. 

Q:  What is the suggested use for HashiScript?
A:  The suggested use is to take two capsules at the same time.  You can take HashiScript at any time during the day; however, most individuals usually take it in the morning.  But an acceptable alternative would be to take one capsule two times daily if you prefer.

Q:  Should I take HashiScript on an empty stomach or with food?
A:  You can take HashiScript without regard to meals; however, HashiScript may work better when you take it on an empty stomach because of the proteolytic enzymes.  But it’s really up to you because there is no wrong time or right time.  HashiScript contains a blend of digestive enzymes, and some work well with food and some on an empty stomach.  Take at your convenience.

Q:  I am usually constipated, but now I’m not.  Could HashiScript be having an affect on my bowels – is that possible?
A:  Yes, the HashiScript formula contains several digestive enzymes that help improve the metabolism of food as it moves through your GI tract.*  Some individuals have reported a harmless discoloration to the stool (usually greenish) and improved regularity.*  If for some reason you experience diarrhea, reduce dosage to 1 capsule daily (rather than 2 caps).

Q:  Can I take HashiScript if I no longer have a thyroid gland?
A:  Yes, because the HashiScript formula is not intended to produce thyroid hormone.*  HashiScript is intended to support immune function, and immune cells reside primarily in your gut.* HashiScript is a full-body antioxidant supplement and has “anti-rusting” properties (catalase and glutathione) that support the breakdown of free radicals, such as peroxide.*  HashiScript will support immune system function whether or not you have a thyroid gland.*

Q:  I am already taking your Thyroid Script.  Can I also take HashiScript or should I switch to HashiScript? 
A:  Yes, you can take both formulas simultaneously in some cases because HashiScript is primarily a digestive enzyme blend, and Thyroid Script is more for adrenals and T4 to T3 conversion.*  There is one duplicate ingredient - it is the selenium.  But even if you take 2  capsules of Thyroid Script and 2 capsules of HashiScript daily, the total daily amount of selenium you would get is only 205 mcg, which is not considered unsafe.  The selenium dosage used in clinical trials is almost always more than 205 mcg, so the combination of both supplements is in a safe margin. Some individuals take up to 400 mcg of selenium daily, as comparison.  Dosing minerals a highly individualized, therefore consider some of the symptoms of excessive selenium and reduce dosage accordingly. Symptoms of excessive selenium to look for include agitation, restlessness, faster heart rate, and diarrhea, which are symptoms consistent with selenium producing excessive thyroid hormone production.  You could always take less of each formula if need be.

Q:  Is it okay to take HashiScript if I take a prescription thyroid medication?   
A:  Yes in most cases however you should consult your practitioner about all supplement changes to your regimen. HashiScript is essentially an antioxidant formula with several digestive enzymes, so there is nothing in HashiScript that should interfere with a prescription medication.* However, we always advise that you consult with your health-care practitioner before you start taking a nutritional supplement.

Keep in mind that with taking HashiScript – as your general health begins to improve – your thyroid function may begin to normalize or regulate itself better and then your prescription medication may feel like it’s too much.  That is why you must remain supervised by your physician so that a prescription dosage can be reduced if necessary. 

Q:  Is it okay to take HashiScript if I am also taking a statin for high cholesterol?
A:  Yes, statins can interfere with selenium absorption (and also coenzyme Q10) so HashiScript could be useful if you are taking a statin, because HashiScript contains selenium.*  Also, if you have lipid peroxidation, then the catalase in HashiScript could be helpful.*  Of course, we advise that you ask your health-care practitioner about taking any nutritional supplement before you begin taking it.

Q:  I have food sensitivities.  Will taking HashiScript help? 
A:  Yes, it should, because HashiScript contains several proteolytic and digestive enzymes that are known to help support digestive health,* especially if you are consuming gluten, casein, or other food antigens in your diet.

Q:  Is there any magnesium stearate or any other stearate in HashiScript?
A:  No, there is no magnesium stearate or any other stearate in this formula.

 Q:  Is HashiScript gluten-free? 
A:  Yes.  All Script Essential products are gluten-free.  Script Essentials strives to have a virtually hypoallergenic product line, but we cannot know every possible allergy every individual might have.  Our products are made with the fewest possible “Other Ingredients."

Q:  Is HashiScript effective if you no longer have a thyroid gland?
A:  Yes, it can still be extremely helpful for the immune system, and other aspects of gut health because it contains several potent antioxidants, and digestive enzymes.

Q:  I am unable to swallow pills. Can I open the HashiScript capsule and mix it with applesauce and consume it this way?
A:  Yes you may, however emptying contents into food may reduce potency of the supplement by up to 30%.

Q:  I have high selenium levels on my blood test. Is HashiScript safe to take?
A:  No, you should avoid it because the formula contains selenium.

Q:  HashiScript is it vegan?
A:  Yes.

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Filter Reviews:
Barbara A.
United States United States

Feelin Good :)

weight and bloat are coming off, digestion improved, overall feeling so much better! I'm a 30 year Hashimotos patient. This is the best supplement I've found that works for me.

Barbara A.
United States United States

Loving this product!

Bloating, digestive issues and overall feeling of “wellness”are improving! Thank you for a good, clean product with no stearates. And thank you for the educational information!

Jennifer B.
United States United States

Changed my life

This supplement honestly gave me back my energy after having my daughter. I was totally exhausted and depleted after going through a tough pregnancy, delivery etc. I felt better with my energy restored 2 weeks after taking this, even with just a half dose. Life changer!

Cheryl C.

I feel better than I have in over a year

I have been sick and progressively getting sicker since 2014. I recently found out my thyroid is enlarged and have multiple nodules. I did some research on YouTube about enlarged thyroid and Hashimoto’s and came across Dr Cohen’s video. Made sense, so I thought I would try some supplements to maybe feel better. I looked on amazon and found Hashi script. After the first dose I immediately started feeling better. I actually got out of the house, had enormous energy and went kayaking.

Ramona M.


I know this sounds crazy, but after taking this for just 1 day, I immediately felt a difference. I was not able to step up 1 step on my porch without having to hang on to the post. I could not even lift my leg without pain, bend my knees (I could not even bend my knees without pain prior to taking Hashiscript). Literally on the second day of taking Hashiscript, I was able to lift my lefg, walk up steps, high knee march in place, jog in place, and just do that old basic thing called walking!!! OMG!!!! I LOVE THIS PRODUCT!!! I am so excited for the furture now. Thank you so much Suzy Cohen.