Mito B Complex with Adeno B12 and 5-MTHF by Suzy Cohen

Mito B Complex

Improve Methylation & Homocysteine*
281 reviews

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The only B complex that gets into your mitochondria! This formula can help maintain normal energy levels and neurological activity* It supports healthy cycles of methylation and homocysteine breakdown. B vitamins are considered ‘anti-stress’ nutrients and help maintain healthy cellular growth and DNA repair.

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Contains the full range of B complex nutrients in their methylated, bioavailable form, including 5-MTHF. Mito B Complex is named as such because it contains the mitochondrial form of various B-vitamin nutrients. It is FREE of synthetic folic acid. May cause a harmless discoloration of urine (yellow) due to riboflavin content.

Helps with optimal absorption of B vitamins which are known to convert food into fuel (ie energy), while supporting healthy nervous system function and myelin sheath due to the B12 which comes in the form of methylcobalamin and adenosylcobalamin.*


Suggested Use: Take 1 or 2 capsules daily with a snack or meal, preferably earlier in the day.



Q: Is this formula gluten-free?
A: Yes, it is free of common allergens, it is also vegan.

Q: Will the niacin cause a heat flush?
A: It may, in sensitive individuals. This is a harmless reaction that is unlikely to occur with Mito B Complex, we’ve heard of this only several times in the 5 years it has been on the market. The ‘niacin flush’ usually occurs with high-dose niacin as that which is found in prescription doses.

The reason it occurs is because the blood vessels dilate, which is considered a good thing. The discomfort of flushing actually plays a useful role. It helps with cholesterol and capillary blood flow.* Mito B Complex contains a very low amount of niacin, so it should not occur, but we want you to know that it might in case you are among the sensitive. Flushing may be minimized by taking niacin with some food or a snack. Do not combine it with alcohol or hot tea/coffee. Furthermore, if you are super sensitive, you may take a baby aspirin about 30 minutes before taking Mito B Complex.

Q: Who should not take B-complex vitamins?
A: If you are taking certain chemotherapy drugs (ie cisplatin), or anti-epileptic medications (such as valproic acid, or phenytoin), taking B complex vitamins isn’t appropriate. Please ask your physician if and when you may take a B-complex pill. Furthermore, some patients who are supported on Levodopa may not be able to tolerate or take B vitamins. Ask your practitioner to be sure it’s right for you.

Q: When is it best to take Mito B Complex?
A: In the morning or early afternoon, otherwise you may experience restlessness or insomnia. B vitamins are known to produce ATP/energy. Q: Can B vitamins cause weight gain?
A: No, the opposite may be true.

Q: How long does it take to feel effects?
A: Usually within a day or two. B vitamins work very quickly to support over 300 metabolic processes in the body, and they transport fuel to all the organs and tissues. Brain clarity may increase as well.*

The Scientifically Studied Ingredients in Mito B-Complex™

Vitamin B2 — as Riboflavin 5-phosphate

Vitamin B2 is so important for healthy brain function and studies suggest it can be indicated for fatigue, leg cramps, and healthy hair and cell growth.* Sadly, plain riboflavin is what's found in practically every B complex supplement on the market. This form is not active. It's a precursor that has to be activated to "Riboflavin 5-Phosphate" in order for it to help you with energy production in the form of ATP.*

In Mito B-Complex, the biologically active R5P is used!

Vitamin B3 — as Niacin and Niacinamide

Vitamin B3 is sedative and calming, because it works as a GABA agonist (similarly to benzodiazepines), but of course it’s a vitamin so it’s mild.* Niacin lowers your stress hormone, cortisol.*

Even individuals with alcohol dependence, conditions of worry and stress, or certain mood problems can respond to the relaxing qualities of niacin.* Niacin (for cholesterol) and niacinamide are not exactly the same. Mito B-Complex contains both of these forms of vitamin B3.

Vitamin B5 — as Pantothenic Acid 

This nutrient in the B complex is a precursor to Coenzyme A, which is also part of your Krebs cycle, and it literally helps you sustain life.* Although a deficiency is rare, it could lead to memory loss due to impaired synthesis of the memory molecule acetylcholine, as well as numbness, parasthesia, adrenal dysfunction, muscle cramps, and low blood sugar.

Pantothenic helps maintain cholesterol levels within the normal range.*

Vitamin B12 — as Adenosylcobalamin 

Mito B-Complex contains TWO types of vitamin B12.Adenosylcobalamin (Adeno B12) is used by the mitochondria, the battery of your cell where ATP (energy) is made.* It happens a million times a minute.

The Krebs cycle produces Methylmalonyl-CoA (converted to Succinyl-CoA). It's right there that Adeno B12 works in your mitochondria to to generate cellular energy.* You're reinventing more energy, every split second! When the Kreb cycle falters, it causes DNA and RNA damage (free radicals), which is connected to fatigue and abnormal cell growth.* Tired mito = tired you!


Biotin makes for more youthful, beautiful hair skin and nails. A deficiency of it is associated with hair loss and red, scaly skin so biotin is sometimes useful for people with rash problems.

Biotin also plays a role in maintaining the normal rhythm of your heartbeat.* There is some evidence to suggest that biotin helps manage blood sugar.*

Vitamin B12 — as Methlycobalamin 

Mito B-Complex contains another form of B12 in addition to adeno-B12 which is described above. It's called Methylcobalamin.* This supports neurological function and the break down of homocysteine.* The CDC has reported that some children with motor and language developmental delays may be B12 deficient! Methylcobalamin deficiency may cause confusion and numbness/tingling. A deficiency impacts the health of your myelin, which is a wrapping around your nerves.*

Vitamin B6 — as Pyridoxal 5’ Phosphate 

The active form of vitamin B6 (as pyridoxal 5’ phosphate, or P5P) can help with menstrual pain, as well as nerve pain issues.* In addition, B6 can support a healthy mood by impacting the way you break down neurotransmitters.* Issues and pain with the tongue, lips and gums may occur without B6. Vitamin B6 doesn't work, it has to be converted in your body to P5P, and Mito B-Complex gives you P5P because it is body-ready. You take it, and it works.

Vitamin B1 (Thiamine) — as Benfotiamine  

Vitamin B1 or thiamine is necessary to make acetylcholine and GABA,* which are your memory compound and sleep/relaxation hormone, respectively. Mito B contains benfotiamine. Benfotiamine is a lipophilic form of vitamin B1 that penetrates your brain neurons about 3 - 4 times better than the plain thiamine!Vitamin B1 also helps your body with alertness, heart rhythm and eye movements. Also, thiamine along with B12, "wrap" each nerve with protective myelin.* Thiamine levels plummet with alcohol consumption.

Vitamin B9 — as Methyl Folate (5-MTHF) 

5-MTHF is a biologically active form of the synthetic B vitamin you have heard of called “folic acid.” I chose 5-MTHF for Mito B-Complex to ensure excellent immediate effects on your methylation pathway and metabolism.*5-MTHF is especially useful for supporting a positive mood and a healthy central nervous system, because it is the only form of vitamin B9 that crosses your blood-brain barrier.* It helps build neurotransmitters in your body to support a good mood as well as myelination (coating) of your nerve fibers.*

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Filter Reviews:
Carol K.
United States United States

Mito B Complex

Have used Mito B Complex for a while and find it works well for me. Will continue purchasing this product from Suzy Cohen.

Tim F.
United States United States

Seems to Help

Seems to help with chronic fatigue issues. Have been able to do more exercise and work for longer periods since starting this product.

Brenda R.
United States United States

Mito B Complex

It helps me feel better. The product is great, but delivery is very slow.

Robert b.
Canada Canada


My wife and I have communication problems in our legs and feet. The MITO B-COMPLEX seemed to help me but my wife still has problems. I ordered enough for a 4 month supply for her. I am using another B-Complex from here in Canada now. It is expensive to order from the U.S.A. We will see in the 4 month time if my wife gets better so that she will be able to feel her feet again without pain, cold and numbness. Thank you Suzy Cohen for your products as I believe they are the best of the best. We are 76 and 85 years old with no health plan.

Marie M.
United States United States

Mito B Complex

This is the only B Complex I will buy...helps withenergy levels.I have a good background in nutritional sciences I am 88 yo and do my own research.I recommend this product and your company to a lot of people....will continue to do so.